Analysis of novel risk factors influencing control of food intake and regulation of body weight

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Research Project: PN-II-ID-PCE-2012-4-0608

Project Type: EXPLORATORY RESEARCH PROJECTS

Contract No.: 48/02.09.2013


Period: September 2013— September 2016

Project Director: Associate Professor Mihai COVASA

Department of Health and Human Development

"Stefan cel Mare" University of Suceava, Romania

E-mail: geman@eed.usv.ro, iulian@eed.usv.ro

Expected outcomes of the project for Stages I, II, III and IV (September, 2013 - September, 2016) Results delivered in the project for Stages I, II, III and IV (September, 2013 - September, 2016) Budget for Stages I, II, III and IV (September, 2013 - September, 2016)
5 articles published / accepted for publication in a journal or conference volume and 6 articles published / accepted for publication in congerences proceedings 5 articles published in international ISI journals,
18 articles published in ISI volumes,
3 articles published in international conference's volumes,
1 book chapter published in an international Publishing House		 Staff cost = 180.440,00 RON
Indirect costs = 37.000,00 RON
Logistical costs = 222.627,47 RON
9 communications at national / international conferences 29 communications at international conferences
1 communication at a national conference 		Travel costs = 54.355,53 RON
2 cooperation agreements 6 concluded cooperation agreements TOTAL fourth stage, year 2016 = 494.423,00 RON
Total Project Value = 1.425.100 RON

Scientific Report - Fourth stage, year 2016

Final Report

Plan for achieving project objectives 2013-2015

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Project activities, expected results, achieved results, allocated budget, 2013-2014

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List of publications and presentations

The results were dissemination according to the project plan, as follows:

ARTICLES:

    >>Stage IV: January - September, 2016

    Book Chapter published in an international Publishing House (INTECH)

  1. Ovidiu Schipor,Oana GEMAN, Iuliana Chiuchisan, Mihai Covasa - From Fuzzy Expert System to Artificial Neural Network: Application to Assisted Speech Therapy, book "Artificial Neural Networks", ISBN 978-953-51-4713-8, 26 pages, Intech Publishing House, 2016. View the book chapter

    2. Articles published in volumes of international conferences


  2. Oana GEMAN, Iuliana Chiuchisan, Mihai Covasa - Data mining and knowledge discovery tools for human microbiome big data, Proceedings of the 6th International Conference on Computers Communications and Control (ICCCC 20016), DOI: 10.1109/ICCCC.2016.7496744, pp. 91-96, Oradea, Romania, May 10-14, 2016. View article
  3. Oana GEMAN, Iuliana Chiuchisan, Mihai Covasa, Cris Doloc, Rodica-Mariana Milici, Laurentiu-Dan Milici - Deep Learning Tools for Human Microbiome Big Data, Proceedings of the 7th International Workshop on Soft Computing Applications (SOFA 2016), Arad, Romania, August 24-26, 2016. View article
  4. Iuliana Chiuchisan, Iulian Chiuchisan, Oana GEMAN, Rodica-Mariana Milici, Laurentiu-Dan Milici - Tremor Measurement System for Neurological Disorders Screening, Proceedings of the 7th International Workshop on Soft Computing Applications (SOFA 2016), Arad, Romania, August 24-26, 2016. View article
  5. Oana GEMAN, Iuliana Chiuchisan, Mihai Covasa, Konstantinos EFTAXIAS, Saeid SANEI, Jonni Guiller Ferreira MADEIRA, Ronney Arismel Mancebo BOLOY - Joint EEG - EMG Signal Processing for Identification of the Mental Tasks in Patients with Neurological Diseases, Proceedings of the 24th European Signal Processing Conference (EUSIPCO), ISSN: 2076-1465, 978-0-9928-6265-7/16/$31.00 ©2016 IEEE, pp. 1598-1602, 28 August - 2 September 2016, Budapest, Hungary. View article

    6. >>Stage III: January - December, 2015

    Articles in international journals ISI:


  6. Frank A. Duca, Shahbaz Katebzadeh, COVASA, M. - Impaired GLP-1 Signaling Contributes to Reduced Sensitivity to Duodenal Nutrients in Obesity-Prone Rats During High-Fat Feeding, Journal OBESITY BIOLOGY AND INTEGRATED PHYSIOLOGY, Obesity (2015) 23, 2260-2268. doi:10.1002/oby.21231, pg. 2260-2268. View article

    7. Articles published in volumes of international conferences ISI/BDI


  7. Oana GEMAN, Saeid Sanei, Hariton-Nicolae Costin, Konstantinos Eftaxias, Oldrich Vysata, Ales Prochazka, Lenka Lhotska - CHALLENGES AND TRENDS IN AMBIENT ASSISTED LIVING AND INTELLIGENT TOOLS FOR DISABLED AND ELDERLY PEOPLE, Proceedings of INTERNATIONAL WORKSHOP ON COMPUTATIONAL INTELLIGENCE FOR MULTIMEDIA UNDERSTANDING - IWCIM 2015, 978-1-4673-8457-5/15/$31.00 ©2015 IEEE, Prague, Czech Republic, 29-30 October 2015. View article
  8. Iuliana Chiuchisan, Iulian Chiuchisan, Mihai Dimian - INTERNET OF THINGS FOR E-HEALTH: AN APPROACH TO MEDICAL APPLICATIONS, Proceedings of INTERNATIONAL WORKSHOP ON COMPUTATIONAL INTELLIGENCE FOR MULTIMEDIA UNDERSTANDING - IWCIM 2015, 978-1-4673-8457-5/15/$31.00 ©2015 IEEE, Prague, Czech Republic, 29-30 October 2015. View article
  9. Sinziana-Calina Silisteanu, Mihai Covasa - ASSISTING THE QUALITY OF LIFE FOR OLD AGE PERSONS (OVER 65 YEARS OLD) WITH DISABILITIE , Proceedings of INTERNATIONAL WORKSHOP ON COMPUTATIONAL INTELLIGENCE FOR MULTIMEDIA UNDERSTANDING - IWCIM 2015, 978-1-4673-8457-5/15/$31.00 ©2015 IEEE, Prague, Czech Republic, 29-30 October 2015. View article
  10. Oana GEMAN, Iuliana Chiuchisan - A Health Care Self-Monitoring System for Patients with Visual Impairment using a Network of Sensors, Proceedings of The 5th IEEE International Conference on E-Health and Bioengineering - EHB 2015, 978-1-4673-7545-0/15/$31.00 ©2015 IEEE, Grigore T. Popa University of Medicine and Pharmacy, Iasi, Romania, November 19-21, 2015. View article
  11. Maria Magdalena Lungu, Anca Bosancu, Oana GEMAN - Mini-review: Human Microbiome Project - Recent Trends and Future Challenges, Proceedings of The 5th IEEE International Conference on E-Health and Bioengineering - EHB 2015, 978-1-4673-7545-0/15/$31.00 ©2015 IEEE, Grigore T. Popa University of Medicine and Pharmacy, Iasi, Romania, November 19-21, 2015. View article
  12. Anca Bosancu, Maria Magdalena Lungu, Oana GEMAN - Trends in Healthy Status among Students in the Department of Health and Human Development, Suceava, Romania, 2013-2015, Proceedings of The 5th IEEE International Conference on E-Health and Bioengineering - EHB 2015, 978-1-4673-7545-0/15/$31.00 ©2015 IEEE, Grigore T. Popa University of Medicine and Pharmacy, Iasi, Romania, November 19-21, 2015. View article
  13. Sinziana-Calina Silisteanu, Mihai Covasa - The importance of nutrition and physical activity in young people increased quality of life, Proceedings of The 5th IEEE International Conference on E-Health and Bioengineering - EHB 2015, 978-1-4673-7545-0/15/$31.00 ©2015 IEEE, Grigore T. Popa University of Medicine and Pharmacy, Iasi, Romania, November 19-21, 2015. View article
  14. Sinziana-Calina Silisteanu, Mihai Covasa - Reduction of Body Weight through Nutrition Intervention Reduces Chronic Low Back Pain, Proceedings of The 5th IEEE International Conference on E-Health and Bioengineering - EHB 2015, 978-1-4673-7545-0/15/$31.00 ©2015 IEEE, Grigore T. Popa University of Medicine and Pharmacy, Iasi, Romania, November 19-21, 2015. View article

    15. >>Stage II: January - December, 2014

    Articles in international journals ISI:


  15. Duca, F. Gérard, P. COVASA, M. Lepage, P. - The metabolic interplay between gut bacteria and their host, Frontiers of Hormone Research, S. Karger Publishers, Basel, Switzerland, 2014. View article
  16. Li Zhong, Xufei Zhang and COVASA M. - Emerging roles of lactic acid bacteria in protection against colorectal cancer, World Journal of Gastroenterology 2014 June 28; 20(24): 7878-7886, ISSN 1007-9327 (print) ISSN 2219-2840 (online), DOI: 10.3748/wjg.v20.i24.7878, Impact Factor ISI: 2,54. (www.wjgnet.com). View article
  17. Duca FA, Swartz TD, COVASA M. - Effect of diet on preference and intake of sucrose in obese prone and resistant rats, PLoS One, 9(10):e111232, 2014. Impact Factor ISI: 3,73. Pubmed Vizualizeaza articolul

    18. Articles published in volumes of international conferences ISI/BDI


  18. COVASA, M., Langelier, B., Douard, V., Devime, F., Lepage, P., Hajnal, A., Biegler, J. - Impact of Roux-en-Y gastric bypass surgery on enteroendocrine cell differentiation, glucose sensing and gut microbiota composition. Program No. 833.06/OO12. Washington DC, Society for Neuroscience, 2014. Neuroscience 2014 Program
  19. COVASA, M. - Dysregulations in regulatory pathways associated with obesity are recapitulated by gut microbiota. American Diabetes Association. Diabetes and the Microbiome Research Symposium. Oct. 29, 2014. Chicago, IL. American Diabetes Association, Diabetes and the Microbiome Research Symposium 2014
  20. Sakar, Y.; Langelier, B.; Devime, F.; COVASA, M. - Impaired enteroendocrine cells differentiation signaling pathways through microbiota transfer. Experimental Biology Abstr # 8894, San Diego, 2014. Program for Experimental Biology 2014
  21. Sakar, Y.; Langelier, B.; Devime, F.; COVASA, M. - HF-feeding-induced endoplasmic reticulum stress links metabolic syndrome. Experimental Biology Abstr # 8834, San Diego, 2014.Program for Experimental Biology 2014
  22. Oana GEMAN, Iuliana Chiuchisan, Andrei Coriolan Iuresi, Iulian Chiuchisan, Mihai Dimian, Anca Bosancu, Daniela Buliga and Mihai COVASA - Intelligent System for a Personalized Diet of Obese Patients with Cancer, Proceedings of the 2014 International Conference and Exposition on Electrical and Power Engineering (EPE2014), Workshop on Electromagnetic Compatibility and Engineering in Medicine and Biology, IEEE Catalog Number: CFP1447S-USB, ISBN: 978-1-4799-5848-1, Iaai, Romania, october 2014. View article
  23. Oana GEMAN, Saeid Sanei, Iuliana Chiuchisan, Adrian Graur, Ales Procházka, and Oldrich Vysata - Towards an Inclusive Parkinson's Screening System, Proceeding of the 18th International Conference on System Theory, Control and Computing (ICSTCC2014), ISBN: 978-1-4799-4602-0, pg. 476-481, Sinaia, Romania, october 2014. View article

    24. >>Stage I: September - December, 2013

    Articles in international journals ISI:

  24. Frank A. Duca, LiZhong, COVASA M. - Reduced CCK signaling in obese-prone rats fed a high fat diet, Hormones and Behavior, 64 (2013) 812-817, Elsevier www.elsevier.com . View article

    25. Articles published in volumes of international conferences

  25. Oana GEMAN - A Markov Model for Analyzing the Health Status of the Romanian Population until 2020, Proceedings of the IEEE International Conference on E-Health and Bioengineering - EHB 2013, 978-1-4799-2373-1, IEEE Xplore®, ISI-Proceedings, SCOPUS and INSPEC (IET) data bases.View article
  26. Lucian-Nicolae Cojocariu, Mihai DIMIAN, Marius Prelipceanu - Developing a wireless electrocardiography device for mobile and at-home healthcare applications, Proceedings of the IEEE International Conference on E-Health and Bioengineering - EHB 2013, 978-1-4799-2373-1, IEEE Xplore®, ISI-Proceedings, SCOPUS and INSPEC (IET) data bases.View article
  27. Florentina-Carmen OLENIUC - The impact of eating behaviour and food preferences on nutritional status, Proceedings of the IEEE International Conference on E-Health and Bioengineering - EHB 2013, 978-1-4799-2373-1, IEEE Xplore®, ISI-Proceedings, SCOPUS and INSPEC (IET) data bases.View article

PRESENTATIONS/COMMUNICATIONS:

    >>Stage IV: January - September, 2016

  1. Oana GEMAN, Iuliana Chiuchisan, Mihai Covasa - Data mining and knowledge discovery tools for human microbiome big data, 6th International Conference on Computers Communications and Control (ICCCC 20016), Oradea, Romania, May 10-14, 2016. Technical program
  2. Oana GEMAN, Iuliana Chiuchisan, Mihai Covasa, Cris Doloc, Rodica-Mariana Milici, Laurentiu-Dan Milici - Deep Learning Tools for Human Microbiome Big Data, 7th International Workshop on Soft Computing Applications (SOFA 2016), Arad, Romania, August 24-26, 2016. Technical program
  3. Iuliana Chiuchisan, Iulian Chiuchisan, Oana GEMAN, Rodica-Mariana Milici, Laurentiu-Dan Milici - Tremor Measurement System for Neurological Disorders Screening, 7th International Workshop on Soft Computing Applications (SOFA 2016), Arad, Romania, August 24-26, 2016. Technical program
  4. Oana GEMAN, Iuliana Chiuchisan, Mihai Covasa, Konstantinos EFTAXIAS, Saeid SANEI, Jonni Guiller Ferreira MADEIRA, Ronney Arismel Mancebo BOLOY - Joint EEG - EMG Signal Processing for Identification of the Mental Tasks in Patients with Neurological Diseases, 24th European Signal Processing Conference (EUSIPCO), 28 August - 2 September 2016, Budapest, Hungary. Technical program

    5. >>Stage III: January - December, 2015

  5. Covasa, M., Duca, F.A., Swartz, T.D. - Gut microbiota restores central neuropeptide deficits present in germ free animals. Abstract D261.I/1167.8. Experimental Biology meeting. San Diego, 2015.
  6. Oana GEMAN, Saeid Sanei, Hariton-Nicolae Costin, Konstantinos Eftaxias, Oldrich Vysata, Ales Prochazka, Lenka Lhotska - CHALLENGES AND TRENDS IN AMBIENT ASSISTED LIVING AND INTELLIGENT TOOLS FOR DISABLED AND ELDERLY PEOPLE, INTERNATIONAL WORKSHOP ON COMPUTATIONAL INTELLIGENCE FOR MULTIMEDIA UNDERSTANDING - IWCIM 2015, Prague, Czech Republic, 29-30 October 2015. Technical program
  7. Iuliana Chiuchisan, Iulian Chiuchisan, Mihai Dimian - INTERNET OF THINGS FOR E-HEALTH: AN APPROACH TO MEDICAL APPLICATIONS, INTERNATIONAL WORKSHOP ON COMPUTATIONAL INTELLIGENCE FOR MULTIMEDIA UNDERSTANDING - IWCIM 2015, Prague, Czech Republic, 29-30 October 2015. Technical program
  8. Sinziana-Calina Silisteanu, Mihai Covasa - ASSISTING THE QUALITY OF LIFE FOR OLD AGE PERSONS (OVER 65 YEARS OLD) WITH DISABILITIE, INTERNATIONAL WORKSHOP ON COMPUTATIONAL INTELLIGENCE FOR MULTIMEDIA UNDERSTANDING - IWCIM 2015, Prague, Czech Republic, 29-30 October 2015. Technical program
  9. Oana GEMAN, Iuliana Chiuchisan - A Health Care Self-Monitoring System for Patients with Visual Impairment using a Network of Sensors, The 5th IEEE International Conference on E-Health and Bioengineering - EHB 2015, Grigore T. Popa University of Medicine and Pharmacy, Iasi, Romania, November 19-21, 2015. Technical program
  10. Maria Magdalena Lungu, Anca Bosancu, Oana GEMAN - Mini-review: Human Microbiome Project - Recent Trends and Future Challenges, The 5th IEEE International Conference on E-Health and Bioengineering - EHB 2015, Grigore T. Popa University of Medicine and Pharmacy, Iasi, Romania, November 19-21, 2015. Technical program
  11. Anca Bosancu, Maria Magdalena Lungu, Oana GEMAN - Trends in Healthy Status among Students in the Department of Health and Human Development, Suceava, Romania, 2013-2015, The 5th IEEE International Conference on E-Health and Bioengineering - EHB 2015, Grigore T. Popa University of Medicine and Pharmacy, Iasi, Romania, November 19-21, 2015. Technical program
  12. Sinziana-Calina Silisteanu, Mihai Covasa - The Importance of Nutrition and Physical Activity in Young People Increased Quality of Life, The 5th IEEE International Conference on E-Health and Bioengineering - EHB 2015, Grigore T. Popa University of Medicine and Pharmacy, Iasi, Romania, November 19-21, 2015. Technical program
  13. Sinziana-Calina Silisteanu, Mihai Covasa - The Study Regarding the Influence of Body Weight in Triggering Low Back Pain Chronic, The 5th IEEE International Conference on E-Health and Bioengineering - EHB 2015, Grigore T. Popa University of Medicine and Pharmacy, Iasi, Romania, November 19-21, 2015. Technical program

    14. >>Stage II: January - December, 2014

  14. COVASA, M., Langelier, B., Douard, V., Devime, F., Lepage, P., Hajnal, A., Biegler, J. - Impact of Roux-en-Y gastric bypass surgery on enteroendocrine cell differentiation, glucose sensing and gut microbiota composition, Program No. 833.06/OO12, Washington DC, Society for Neuroscience, 2014. Neuroscience 2014 Program
  15. COVASA, M. - Dysregulations in regulatory pathways associated with obesity are recapitulated by gut microbiota, American Diabetes Association, Diabetes and the Microbiome Research Symposium, Chicago, Oct. 29, 2014. American Diabetes Association, Diabetes and the Microbiome Research Symposium 2014
  16. Duca, F.A., Sakar, Y., Lepage, P., Langelier, B., Devime, F., Dore J., COVASA, M. - Gut microbiota encodes signaling pathways signatures involved in control of food intake and regulation of body weight, 2nd World Congress on targeting microbiota, Pasteur Institute, Paris, France, Oct 16, 2014. 2nd World Congress on targeting microbiota
  17. Duca, F.A., Sakar, Y., Langelier, B., Devime, F., Lepage, P., Dore J., COVASA, M. - Replication of obesity and associated signaling pathways through gut microbiota transfer, National Institute of Health, NIDDK, Host-Microbiota Interactions: how host physiology and disease pathophysiology are affected by the gut microbiota, Bethesda, DC, Sept 2, 2014. Host-Microbiota Interactions
  18. Sakar, Y.; Langelier, B.; Devime, F.; COVASA, M. - Impaired enteroendocrine cells differentiation signaling pathways through microbiota transfer, Experimental Biology Abstr # 8894, San Diego, 2014. Program for Experimental Biology 2014
  19. Sakar, Y.; Langelier, B.; Devime, F.; COVASA, M. - HF-feeding-induced endoplasmic reticulum stress links metabolic syndrome, Experimental Biology Abstr # 8834, San Diego, 2014. Program for Experimental Biology 2014
  20. Oana GEMAN, Saeid Sanei, Iuliana Chiuchisan, Adrian Graur, Ales Procházka, and Oldrich Vysata - Towards an Inclusive Parkinson's Screening System, The 18th International Conference on System Theory, Control and Computing (ICSTCC2014), Sinaia, România, October 17-19, 2014. Technical program for Conference ICSTCC, Sinaia 2014
  21. Oana GEMAN, Iuliana Chiuchisan, Andrei Coriolan Iuresi, Iulian Chiuchisan, Mihai Dimian, Anca Bosancu, Daniela Buliga and Mihai COVASA - Intelligent System for a Personalized Diet of Obese Patients with Cancer, 2014 International Conference and Exposition on Electrical and Power Engineering, Faculty of Electrical Engineering, "Gheorghe Asachi" Technical University of Iasi, Romania, October 16-18, 2014. Technical program for Conference EPE Iasi, 2014
  22. Oana GEMAN, Anca Bosancu, Daniela Buliga - Information system for a personalized diet of obese patients (abstract), Medical Conference "Sf. Doctori Cosma si Damian" Municipal Hospital Days, Radauti, Romania, October 30 - November 01, 2014. Technical Program for Medical Conference, Radauti 2014

    23. >>Stage I: September - December, 2013

  23. Frank A Duca, COVASA M. - Role of GLP-1 and CCK in reduced responsiveness to intestinal nutrients in high-fat fed obese-prone rats , Society for Neuroscience, San Diego, USA, November 9-13, 2013. Neuroscience 2013 Program
  24. Yassine Sakar, COVASA M. - Impact of high-fat feeding on basic helix-loop-helix transcription factors controlling enteroendocrine cell differentiation, Society for Neuroscience, San Diego, USA, November 9-13, 2013. Neuroscience 2013 Program
  25. Duca, F., Swartz, T., Sakar, Y., COVASA M. - Preserved adiposity in the Fisher 344 rat devoid of gut microbiota, Abstract # 6537, Experimental Biology, Boston, April, 2013. Technical Program for Experimental Biology 2013
  26. Duca, F., COVASA M. - Reduced responsiveness to intraintestinal nutrients in obese-prone rats fed high-fat diet, Abstract # 6525, Experimental Biology, Boston, April, 2013. Technical Program for Experimental Biology 2013
  27. COVASA M., Duca, F., Sakar, Y. - Modulation of intestinal signaling by gut microbiota, 33rd Blankenese Conference, Hamburg, Germany, May 25-29, 2013. Technical Program for 33rd Blankenese Conference 2013
  28. Oana GEMAN - A Markov Model for Analyzing the Health Status of the Romanian Population until 2020, The 4th IEEE International Conference on E-Health and Bioengineering - EHB 2013, Grigore T. Popa University of Medicine and Pharmacy, Iasi, Romania, November 21-23, 2013. Technical program for Conference EHB, Iasi 2013
  29. Lucian-Nicolae Cojocariu, Mihai DIMIAN, Marius Prelipceanu - Developing a wireless electrocardiography device for mobile and at-home healthcare applications, The 4th IEEE International Conference on E-Health and Bioengineering - EHB 2013, Grigore T. Popa University of Medicine and Pharmacy, Iasi, Romania, November 21-23, 2013. Technical program for Conference EHB, Iasi 2013
  30. Florentina-Carmen OLENIUC - The impact of eating behaviour and food preferences on nutritional status, The 4th IEEE International Conference on E-Health and Bioengineering - EHB 2013, Grigore T. Popa University of Medicine and Pharmacy, Iasi, Romania, November 21-23, 2013. Technical program for Conference EHB, Iasi 2013